Работаем исключительно с юридическими лицами и государственными предприятиями

Работаем исключительно с юридическими лицами и государственными предприятиями

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BAPTA-AM

14 925,00 ₽

BAPTA-AM (1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester)); ≥ 95% HPLC; BAPTA-AM inhibits free radical-mediated toxicity, enhances apoptosis in non-neuronal cells and protects neurons from ischemic damage;

Категория: Биоактивные малые молекулы

Описание

Описание:

BAPTA-AM inhibits free radical-mediated toxicity, enhances apoptosis in non-neuronal cells and protects neurons from ischemic damage. It regulates ion channels and blocks neuronal Ca2+-activated K+ channel currents. BAPTA-AM maintains intracellular Ca2+ homeostasis.

Применение:

BAPTA-AM has been used :to reduce the elevation of cleaved caspase-3to block cell death, inhibit ROS (reactive oxygen species) production and inhibit caspase-8 activationto exclude the effect of changes in intracellular Ca2+ ([Ca2+]i) concentration during seizure inductionto eliminate the increase of [Ca2+]i induced by 6-hydroxydopamine (6-OHDA)