iCRT3

Описание:

iCRT3 is a small cell-permeable oxazole compound. It blocks cytokine secretion in lipopolysaccharide (LPS)-stimulated macrophages.

Применение:

iCRT3 has been used to inhibit the interactions between β-catenin and transcription factor (TCF). iCRT3 has been used:for β- catenin inhibition in dual luciferase assayto inhibit β-catenin /TCF interactions and their transcriptional activityas wingless/tailess (wnt) antagonist, to determine Wnt/β-catenin signaling is essential for PROX1-mediated regulation of forkhead box protein C2 (FOXC2)(3)catenin inhibition in dual luciferase assayto inhibit β- catenin /TCF interactions and their transcriptional activityas wingless/tailess (wnt) antagonist, to determine Wnt/β-catenin signaling is essential for PROX1-mediated regulation of forkhead box protein C2 (FOXC2)