BAPTA-AM

Описание:

BAPTA-AM inhibits free radical-mediated toxicity, enhances apoptosis in non-neuronal cells and protects neurons from ischemic damage. It regulates ion channels and blocks neuronal Ca2+-activated K+ channel currents. BAPTA-AM maintains intracellular Ca2+ homeostasis.

Применение:

BAPTA-AM has been used :to reduce the elevation of cleaved caspase-3to block cell death, inhibit ROS (reactive oxygen species) production and inhibit caspase-8 activationto exclude the effect of changes in intracellular Ca2+ ([Ca2+]i) concentration during seizure inductionto eliminate the increase of [Ca2+]i induced by 6-hydroxydopamine (6-OHDA)